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Applications of Automation in Research and Clinical Diagnostics

Published

2 months ago

May 18, 2024

Precision counts in the fields of science and medicine. This is particularly true for the basic task of counting and analyzing cells, which is used in both clinical and research settings. The introduction of automatic cell counters, which provide efficiency and accuracy that manual approaches cannot match, has resulted in a notable advancement in this field.

What is Automated Cell Counting?

Automated cell counters are advanced instruments that are made to precisely and swiftly count and examine cells. In contrast to manual counting methods that rely on human vision and a microscope, automated counters use software algorithms and image technology to count and analyze cells. This ensures more accurate findings by expediting the procedure and lowering the possibility of human error.

Type of Automated Cell Counters

There are several types of automated cell counters used in research and clinical diagnostics, each employing different technologies and methods for cell counting. The main types of automated cell counters include:

● Image Cytometers: These devices use optical microscopy to statically image cells, which are frequently labeled to detect certain molecules or provide contrast. Cell counting is aided by the automation of image cytometers made possible by digital cameras.

● Flow Cytometers: Use a regulated flow of suspended cells to align individual cells for analysis. Staining cells with fluorochromes enables visual characterization of the cells and facilitates high-throughput analysis.

● Cell Sorters: Arrange cells according to their electrical properties. Sorting is accomplished by dividing the fluid stream containing the cells into droplets whose electrical charge varies according to the kind of cell and guiding them into various containers.

● Time-Lapse Cytometers: Allow for continuous monitoring of cells in an incubator by employing non-heat-generating light sources, such as LEDs, in conjunction with image cytometry to investigate cellular dynamics without causing damage to living cells.

● Hemocytometers: A qualified technician, an optical microscope, and a gridded slide with known volume wells are used in this manual cell counting approach. Up until the 1950s, hemocytometers were the norm for counting cells.

These various types of automated cell counters provide effective and precise methods for cell counting and analysis, each with unique benefits and uses in clinical and research environments.

Research

Automated cell counters have become indispensable tools in understanding cell behavior. They are used in various research fields, including cancer research, drug discovery, and stem cell therapy.

One of the key benefits in research is the ability to handle large volumes of data. For instance, in drug discovery, automated counters can quickly analyze the effects of thousands of compounds on cell growth and death. This high-throughput capability accelerates the pace of research, allowing scientists to screen potential drugs more efficiently than ever before.

Moreover, automated cell counters offer the precision required to detect subtle changes in cell populations. This is crucial in fields like cancer research, where understanding the behavior of cancer cells can lead to the development of more effective treatments.

Clinical Diagnostics

The impact of automated cell counters extends beyond the research laboratory and into clinical diagnostics. In medical laboratories, these devices play a critical role in routine blood tests, infectious disease diagnostics, and monitoring patient health during treatment.

For example, in a routine complete blood count (CBC), automated cell counters can quickly provide a detailed analysis of different blood cell types. This information is vital for diagnosing conditions such as anemia, infections, and blood cancers. The speed and accuracy of automated counters mean that patients can receive diagnoses and begin treatment more swiftly.

In the context of infectious diseases, automated counters can detect and quantify specific pathogens or immune cells, helping to diagnose infections quickly and accurately. During the COVID-19 pandemic, automated cell counting technologies were instrumental in monitoring virus spread and patients’ immune responses, showcasing their value in crisis situations.

Challenges and Future Directions

The initial cost of these devices can be high, and their operation requires specific technical expertise. Additionally, different types of cells and conditions may require customized counting protocols, necessitating ongoing adjustments and updates to software algorithms.

Looking ahead, ongoing advancements in technology promise to further enhance the capabilities of automated cell counters. The global cell counting market growth is anticipated at a CAGR of 7.5% by 2032. Innovations in imaging technology, artificial intelligence, and machine learning are expected to improve accuracy, speed, and the ability to analyze more complex cell characteristics. As these technologies evolve, automated cell counters will become even more integral to research and diagnostics, opening new avenues for scientific discovery and patient care.

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6 Reasons to Try Cannabis Edibles

Published

1 year ago

February 21, 2023

Jimmy Lerner

Are you looking for a reason to try cannabis edibles? If you’re wondering if there are benefits to edibles that you can’t get with other forms of cannabis, the answer is yes. Here are some of the best reasons to try cannabis edibles.

Some edibles are boosted

When you smoke cannabis flower, you’re only getting cannabis. That’s not a bad thing, but there are brands that sell edibles that have been boosted with other ingredients. For instance, you’ve probably seen capsules with added herbs to help you sleep – the same is true for edibles.

One of the newer enhanced cannabis edibles are the Bits adaptogen-boosted edibles. These new cannabis edibles contain just 5mg of THC per Bit so you don’t overdo anything. Each flavor is packed with a unique blend of adaptogens like ashwagandha, reishi, elderflower, lemon balm, ginseng, guarana, and rose hip.

Why adaptogens? Adaptogens have been proven to have a positive impact on the central nervous system by decreasing sensitivity to stressors. In other words, adaptogens reduce stress and anxiety and contribute to an overall sense of wellbeing. When you consume cannabis edibles boosted by adaptogens, you’re going to feel more relaxed.

Edibles provide precise and consistent dosing

One of the best reasons to try edibles is for precise and consistent dosing. When edibles are made, the cannabis is thoroughly and evenly mixed in, so each serving has the intended dosage when the final product is made. In addition, premium cannabis brands like Verano lab test each batch to ensure quality and consistency with all of their products, including cannabis edibles.

When you smoke flower, you won’t always get the same amount of THC. It’s nearly impossible to know how much THC or CBD you’re getting from smoking flower. Even when you smoke the same strain in the same amount, the THC and other cannabinoids are distributed unevenly throughout each bud.

If precise and consistent dosing is important to you, then edibles are going to be your favorite cannabis delivery method.

Edibles are tasty

Edibles taste good, so why not try them? It’s just like eating a snack or a treat, but with a purpose. If you’ve avoided trying cannabis tinctures or oil because you don’t like the flavor, that’s understandable. Edibles are different because the taste of cannabis itself can be easily masked.

Brands go out of their way to come up with recipes that taste good because they know some people don’t like the strong flavor of cannabis. Edibles like brownies, cookies, and chocolate bars usually just taste like any other cookie, brownie, or chocolate bar. Premium cannabis brands will also use quality ingredients to produce the best cannabis-infused gummies, hard candies, and baked goods.

Edibles are easy to carry

If you want to carry your cannabis around discreetly, that’s easiest with edibles. They usually come in smaller packages that you can fit into a pocket or bag, and edibles are easy to eat without anyone suspecting you’re consuming cannabis.

When carrying edibles, be smart about where you bring them. Make sure you know where you can and can’t have them. If you’re headed to the airport of a government building, for example, you’ll want to leave your edibles at home.

The effects of edibles last for a long time

Smoking flower is great when you need relief quickly, but when you want the effects to last a long time, edibles are your best option. When you ingest cannabis, it takes longer for the effects to kick in, but those effects will last for a much longer time. You also don’t need to consume as much cannabis to get these long-lasting effects.

Everyone is different, and the timing depends on a multitude of factors like our metabolism and whether you’ve eaten or have an empty stomach. However, in general, it takes between 30 minutes and 4 hours to start feeling the effects of edibles. From there, the effects can last a few hours or even up to twelve hours. This is why many people take edibles before going to bed – getting that full impact while they sleep makes them wake up feeling incredibly rested.

Edibles are a great alternative to smoking

Although smoking cannabis is probably the most popular consumption method, it’s not for everyone. Edibles won’t expose you to the potentially harmful effects of smoking. If you’ve been avoiding trying cannabis because you thought you had to smoke it, edibles are the perfect opportunity for you to try cannabis.

Already familiar with edibles? Try something new

If you’ve been consuming cannabis edibles for a while, maybe it’s time to try something new. If you’ve always been into baked goods, branch out and try some beverages, chocolate bars, or even an adaptogen-boosted cannabis gummy for example. There are plenty of edibles to choose from so you can be sure you’ll find something new that you can enjoy.