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It All Stems from Love

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When she arrived in California from New York, Kathleen “Frankie” Francesca wanted to make a difference. Her dream job—working for a modeling agency in New York—had turned out to be an unfulfilling pit stop.

While supporting her parents, both of whom have diabetes, Frankie began to volunteer with the American Diabetes Association (ADA). After attending ADA committees and recognizing within herself the desire to help others, she decided to enter the world of medicine.

Meanwhile, the occurance of a family hardship meant Frankie had to sell everything she had. Her father was laid off at work and then had to recover from an accident; her mother had to stay home to take care of him and help Frankie with her daughter, as she had just become a single mother. There was something Frankie’s mother would say to her that rang true, even in times like these:

As long as you are breathing, there is always hope.”

Frankie lost neither her hope nor her compassion. Her goal was to begin working at R3 Regenerative Medicine (R3), a company that helps doctors obtain turnkey operations for stem cell clinics. Starting out, she had no phone and no computer. For the internet access she needed to be able to do her job, she was continuously going to libraries.

“I couldn’t tell the CEO that I didn’t have anything,” says Frankie. It wasn’t until two years ago that she did tell them about her initial struggle and lack of resources. Today, she is grateful that the CEO of R3 took a chance on her.

Five years later, she is Chief Operating Officer, and Vice President and partner at R3 Medical Training. She is doing the kind of work that she came to California longing to do: helping people, educating them, and changing the way they live their lives.

“Doctors use [stem cell regenerative medicine] to avoid surgeries or help slow the progression of any existing conditions,” says Frankie. “Anywhere from diabetes to neurological issues and joint issues. There’s a lot that you can do with stem cells.”

Frankie is a single mother to her 9-year-old daughter, Valentina. When she isn’t at work, she is spending time with her. They travel together, too, but working seven days a week means that she doesn’t have much extra time.

“I feel bad having to leave her when I have to travel for work,” says Frankie. “But at least I’m leaving my daughter knowing that I’ve done something that I can be proud of, and she can be proud [realizing] how much of a difference her mother made in those people’s lives.”

Where R3 was once a small marketing company, there are now 43 affiliated clinics across the United States and eight internationally. They are opening their own headquarters and anti-aging clinic in Scottsdale this September, a clinic in Nashville in November, and soon another in India. Frankie is preparing for their very first Health and Wellness Summit in Temecula this January—which will not be without celebrities.

One clinic, co-owned by Frankie, recently opened in the Philippines. She is especially excited to start visiting this location; she has family there, and has not been back in 25 years. With the opening of this location, she will be able to visit a few times a year.

“I’m looking forward to bringing my daughter so that she can learn the culture,” says Frankie. She is planning a trip for as soon as January 2022.

Currently, Frankie is in the process of finalizing a memoir, which she has written to tell her story to both her daughter and generations to come. She is not writing the book with commercial success in mind; rather, it is a heartfelt gesture to her daughter, a vessel meant to preserve important memories. She wants her daughter to know her journey, including how she dealt with negativity on the way.

“Especially as a single mom, you know, being Filipino, back in the day, we’re kind of looked down upon,” says Frankie. “Getting to where I’m at now in life, [I’m] supporting my family, giving my daughter everything that she can ever hope for.”

Frankie moves through life with a big heart and an eye on the future. She wants everyone to know that they can achieve a lot more than they think is possible, if they do as she did: keep at what you’re passionate about, don’t lose sight of the bigger picture, and in her words, be “willing to sweat bullets.”

Rosario is from New York and has worked with leading companies like Microsoft as a copy-writer in the past. Now he spends his time writing for readers of BigtimeDaily.com

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Lifestyle

Wanda Knight on Blending Culture, Style, and Leadership Through Travel

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The best lessons in leadership do not always come from a classroom or a boardroom. Sometimes they come from a crowded market in a foreign city, a train ride through unfamiliar landscapes, or a quiet conversation with someone whose life looks very different from your own.

Wanda Knight has built her career in enterprise sales and leadership for more than three decades, working with some of the world’s largest companies and guiding teams through constant change. But ask her what shaped her most, and she will point not just to her professional milestones but to the way travel has expanded her perspective. With 38 countries visited and more on the horizon, her worldview has been formed as much by her passport as by her resume.

Travel entered her life early. Her parents valued exploration, and before she began college, she had already lived in Italy. That experience, stepping into a different culture at such a young age, left a lasting impression. It showed her that the world was much bigger than the environment she grew up in and that adaptability was not just useful, it was necessary. Those early lessons of curiosity and openness would later shape the way she led in business.

Sales, at its core, is about connection. Numbers matter, but relationships determine long-term success. Wanda’s time abroad taught her how to connect across differences. Navigating unfamiliar places and adjusting to environments that operated on different expectations gave her the patience and awareness to understand people first, and business second. That approach carried over into leadership, where she built a reputation for giving her teams the space to take ownership while standing firmly behind them when it mattered most.

The link between travel and leadership becomes even clearer in moments of challenge. Unfamiliar settings require flexibility, quick decision-making, and the ability to stay calm under pressure. The same skills are critical in enterprise sales, where strategies shift quickly and no deal is ever guaranteed. Knight learned that success comes from being willing to step into the unknown, whether that means exploring a new country or taking on a leadership role she had not originally planned to pursue.

Her travels have also influenced her eye for style and her creative pursuits. Fashion, for Wanda, is more than clothing; it is a reflection of culture, history, and identity. Experiencing how different communities express themselves, from the craftsmanship of Italian textiles to the energy of street style in cities around the world, has deepened her appreciation for aesthetics as a form of storytelling. Rather than keeping her professional and personal worlds separate, she has learned to blend them, carrying the discipline and strategy of her sales career into her creative interests and vice versa.

None of this has been about starting over. It has been about adding layers, expanding her perspective without erasing the experiences that came before. Wanda’s story is not one of leaving a career behind but of integrating all the parts of who she is: a leader shaped by high-stakes business, a traveler shaped by global culture, and a creative voice learning to merge both worlds.

What stands out most is how she continues to approach both leadership and life with the same curiosity that first took her beyond her comfort zone. Each new country is an opportunity to learn, just as each new role has been a chance to grow. For those looking at her path, the lesson is clear: leadership is not about staying in one lane; it is about collecting experiences that teach you how to see, how to adapt, and how to connect.

As she looks to the future, Wanda Knight’s compass still points outward. She will keep adding stamps to her passport, finding inspiration in new cultures, and carrying those insights back into the rooms where strategy is shaped and decisions are made. Her legacy will not be measured only by deals closed or positions held but by the perspective she brought, and the way she showed that leading with a global view can change the story for everyone around you.

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