Health

Study Suggests Maintaining Klotho Protein Levels Protects Against ALS-Related Nerve Degeneration

Published

4 years ago

March 26, 2021

Amyotrophic lateral sclerosis, also known as ALS or Lou Gherig’s Disease after the famous baseball player who was forced to retire after experiencing the disease, is a fatal neurodegenerative disease. The medical term for ALS accurately describes the effects the disease has on patients. Amyotrophic refers to three root terms: a meaning “no,” myo meaning “muscle,” and trophic meaning nourishment, all of which combine to indicate that the condition leads to no nourishment of muscle tissue and atrophy, or wasting away, of the affected tissue. Lateral indicates the upper and lower areas of the spinal cord that lead to muscle atrophy, and sclerosis refers to the hardening and scarring of the affected regions.

In ALS, motor neurons that provide an essential connection between the brain and spinal cord and the rest of the body degenerate or deteriorate rapidly. When the motor neurons eventually die, the brain can no longer cause or control muscle movement, leading to their eventual atrophy. Soon after, individuals can experience partial or total paralysis of voluntary muscles, leading to an inability to control muscle movement, speak, eat, and even breathe. The average life expectancy after receiving an ALS diagnosis is between three and five years.

Lack of Available Treatments

Currently, there is no cure for ALS. While familial, or inherited, ALS accounts for some cases of the disease, nearly 95% of cases occur sporadically, without any known genetic precursor.

In an effort to find a potential preventive treatment for ALS and other neurodegenerative diseases, researchers at Boston University’s School of Medicine have turned to study biological models that simulate neurodegenerative conditions. As a result, scientists have identified a certain protein that appears to serve a unique, beneficial purpose in protecting the brain from the mechanisms of ALS.

Klotho Protein

In Boston University’s School of Medicine laboratory model, researchers identified an anti-aging protein called klotho protein that showed neuroprotective effects. In fact, increasing klotho protein levels reduced neurological deficits in experimental models of both Alzheimer’s Disease and multiple sclerosis (MS). Researchers then posited that klotho protein increases may aid in protecting the brain against other neurodegenerative diseases, as well.

In a subsequent study on a laboratory model, klotho protein provided similar neuroprotective effects against ALS. Klotho protein was shown to reduce ALS-associated neurological deficits, thus providing a potential decrease in the manifestation of symptoms. In conjunction with the presence of anti-inflammatory brain cells called microglia, klotho protein shows potential to protect the brain against inflammation, degeneration, and motor neuron loss.

Future Implications

Klotho protein therapy, along with other activities that increase klotho levels, have been shown to potentially prolong the life of an ALS patient by as much as 300 days. Further, increasing klotho levels appears to improve quality of life by reducing ALS symptoms in patients who have already discovered the disease.

While the klotho protein has long shown benefits for other neurodegenerative diseases, this new information provides hope and potential therapeutic applications for the thousands of patients currently suffering from ALS.

Resources:

https://www.eurekalert.org/pub_releases/2019-06/buso-pop062719.php
https://link.springer.com/article/10.1007/s12031-019-01356-2
https://www.als.org/understanding-als/what-is-als

Health

Snack Smarter: The Rise of Low-Calorie Almond Butter for Active Lifestyles

Published

2 weeks ago

June 10, 2025

Michelle Langton

The snack aisle is shifting. For those who balance a busy life with a commitment to health and fitness, the rise of low-calorie almond butter offers a new way to snack smarter. American Dream Nut Butter is at the center of this change, blending clean ingredients with dessert-inspired flavors and added protein to create almond butter that is both nutritious and enjoyable.

Why Almond Nut Butter Is Key to Clean Eating

As consumers become more mindful of their food choices, the spotlight is increasingly on nutrient-dense snacks that provide sustained energy without excess calories. Almond butter, especially in low-calorie varieties, meets this demand by offering a rich source of healthy fats, fiber, and protein in a compact form. Compared to traditional spreads, such as peanut butter, almond butter often provides a smoother, lighter alternative with a different nutritional profile.

For those who track macros or embrace meal prepping, almond nut butter fits neatly into their plans. Its balance of fats and protein supports satiety, helping to keep hunger at bay between meals or during workouts. American Dream Nut Butter elevates this concept with high-protein options that blend the wholesome qualities of almonds with a subtle sweetness inspired by classic desserts.

How Much Protein is in Low Calorie Almond Butter for High Performance?

One common question around almond butter is: how much protein does almond butter contain? While natural almond butter provides a moderate protein boost, American Dream Nut Butter takes it a step further by creating blends that enhance protein content without relying on artificial sweeteners or fillers. This approach suits those seeking fuel for recovery or sustained energy throughout their day.

These protein-enhanced almond butters can work as a pre-workout snack, a post-exercise treat, or simply as a midday pick-me-up that aligns with a health-conscious lifestyle. The brand’s small-batch production method ensures each jar maintains a fresh, creamy texture that spreads easily or drizzles beautifully over everything from oatmeal to fruit.

Buy Almond Butter: Unique Flavors from American Dream

American Dream Nut Butter distinguishes itself with unique flavor profiles, such as Cinnamon Toasties and Cookie Batter. These offerings embrace the idea that healthful snacks can still delight the palate, using clean, natural ingredients to create indulgent taste experiences without sugar bombs or artificial additives. Each batch is hand-whipped in-house, reflecting the brand’s commitment to quality and care.

Their dedication to natural flavors and nutrient density allows consumers to enjoy a dessert-inspired snack while keeping their wellness goals intact. Whether you’re looking to buy almond butter that tastes like a treat or are curious where you can find almond butter crafted with both nutrition and flavor in mind, American Dream Nut Butter offers an accessible option.

Almond Nut Butter: Fuel for Athletes and Busy Parents

Almond butter’s versatility makes it appealing for a wide range of active lifestyles. For athletes, it provides a balanced blend of nutrients that supports energy and recovery without unwanted additives. For busy parents or professionals juggling multiple demands, it’s a convenient, clean snack that fits into hectic schedules without compromise.

The brand’s YouTube channel offers video insight into how these nut butters are crafted, revealing the hands-on process that ensures quality in every jar. By choosing American Dream Nut Butter, consumers support a product that embodies family values and a personal story of overcoming dietary challenges to create wholesome alternatives that everyone can enjoy.

Where Can You Find the Best Almond Butter & More? The Future Is Here

The growing interest in low-calorie nut butter reflects a broader shift in how people approach snacking—valuing nutrition, flavor, and mindful eating in equal measure. American Dream Nut Butter’s approach, which combines protein-rich formulas with all-natural ingredients and enticing flavors, shows how almond butter, peanut butter, and cashew butter can evolve from a niche health food into a daily staple for those who want to snack smarter.

For more on the evolving nut butter market and how it aligns with fitness trends, check out this feature on the rise of healthy high-protein nut butter. To explore American Dream Nut Butter’s full collection and shop their almond butter selections, visit their website.

American Dream Nut Butter invites you to experience healthy nut butters that strikes a balance between enjoyment and mindful nutrition—perfect fuel for active days and wellness routines alike.

*Images sourced from American Dream Nut Butter