Health

Study Suggests Maintaining Klotho Protein Levels Protects Against ALS-Related Nerve Degeneration

Published

3 years ago

March 26, 2021

Amyotrophic lateral sclerosis, also known as ALS or Lou Gherig’s Disease after the famous baseball player who was forced to retire after experiencing the disease, is a fatal neurodegenerative disease. The medical term for ALS accurately describes the effects the disease has on patients. Amyotrophic refers to three root terms: a meaning “no,” myo meaning “muscle,” and trophic meaning nourishment, all of which combine to indicate that the condition leads to no nourishment of muscle tissue and atrophy, or wasting away, of the affected tissue. Lateral indicates the upper and lower areas of the spinal cord that lead to muscle atrophy, and sclerosis refers to the hardening and scarring of the affected regions.

In ALS, motor neurons that provide an essential connection between the brain and spinal cord and the rest of the body degenerate or deteriorate rapidly. When the motor neurons eventually die, the brain can no longer cause or control muscle movement, leading to their eventual atrophy. Soon after, individuals can experience partial or total paralysis of voluntary muscles, leading to an inability to control muscle movement, speak, eat, and even breathe. The average life expectancy after receiving an ALS diagnosis is between three and five years.

Lack of Available Treatments

Currently, there is no cure for ALS. While familial, or inherited, ALS accounts for some cases of the disease, nearly 95% of cases occur sporadically, without any known genetic precursor.

In an effort to find a potential preventive treatment for ALS and other neurodegenerative diseases, researchers at Boston University’s School of Medicine have turned to study biological models that simulate neurodegenerative conditions. As a result, scientists have identified a certain protein that appears to serve a unique, beneficial purpose in protecting the brain from the mechanisms of ALS.

Klotho Protein

In Boston University’s School of Medicine laboratory model, researchers identified an anti-aging protein called klotho protein that showed neuroprotective effects. In fact, increasing klotho protein levels reduced neurological deficits in experimental models of both Alzheimer’s Disease and multiple sclerosis (MS). Researchers then posited that klotho protein increases may aid in protecting the brain against other neurodegenerative diseases, as well.

In a subsequent study on a laboratory model, klotho protein provided similar neuroprotective effects against ALS. Klotho protein was shown to reduce ALS-associated neurological deficits, thus providing a potential decrease in the manifestation of symptoms. In conjunction with the presence of anti-inflammatory brain cells called microglia, klotho protein shows potential to protect the brain against inflammation, degeneration, and motor neuron loss.

Future Implications

Klotho protein therapy, along with other activities that increase klotho levels, have been shown to potentially prolong the life of an ALS patient by as much as 300 days. Further, increasing klotho levels appears to improve quality of life by reducing ALS symptoms in patients who have already discovered the disease.

While the klotho protein has long shown benefits for other neurodegenerative diseases, this new information provides hope and potential therapeutic applications for the thousands of patients currently suffering from ALS.

Resources:

https://www.eurekalert.org/pub_releases/2019-06/buso-pop062719.php
https://link.springer.com/article/10.1007/s12031-019-01356-2
https://www.als.org/understanding-als/what-is-als

Health

How Circuhealth Clinic’s Treatment Will Benefit You: A Comprehensive Guide

Published

2 weeks ago

July 15, 2024

Michelle Langton

Maintaining optimal health can be challenging in the modern world. Busy lifestyles, poor dietary habits, and the stress of daily life can all contribute to a decline in our overall well-being. Circuhealth Clinic Clinic, led by the renowned Nadia Nassif, offers a holistic approach to health by improving circulatory health through various advanced, non-invasive treatments.

The Importance of Circulatory Health

Circulatory health is fundamental to overall wellness. The circulatory system is responsible for delivering oxygen and nutrients to every cell in the body and removing waste products. When this system is compromised, it can lead to a host of health issues, including chronic fatigue, poor skin health, and even cardiovascular diseases. Improving circulation can enhance energy levels, support organ function, and promote overall vitality.

Personalized Exercise Programs

One of the cornerstones of Circuhealth Clinic’s approach is the creation of personalized exercise programs. These programs are not one-size-fits-all; instead, they are tailored to meet the unique needs of each individual. Personalized exercise programs can significantly enhance circulatory health by boosting blood flow, which delivers essential nutrients and oxygen to tissues and organs.

For instance, regular physical activity strengthens the heart, improves circulation, and helps regulate weight. A tailored exercise program can reduce the risk of injuries, increase motivation by aligning with specific fitness goals, and provide consistent progress tracking for optimal results. This personalized attention ensures that you are not only getting fitter but also healthier in the most efficient way possible.

Detoxification Treatments

Detoxification treatments are another vital aspect of Circuhealth Clinic’s offerings. These treatments are designed to remove toxins that impair circulation, thus enhancing overall health. Circuhealth Clinic detoxification protocols include Hydration Therapy, Detox Diets, Herbal Supplements, and antioxidant consumption.

Hydration Therapy: Drinking plenty of water and hydrating fluids helps flush out toxins, promoting better circulation.
Detox Diets: Consuming a diet rich in fruits, vegetables, and whole grains, while avoiding processed foods and sugars, supports the body’s natural detoxification processes.
Herbal Supplements: Using herbs like milk thistle, dandelion root, and burdock root, known for their detoxifying properties, supports liver function and toxin elimination.

By incorporating these detoxification treatments, Circuhealth Clinic helps to ensure that your body is free from harmful toxins, thus improving circulatory health and overall well-being.

Stress Reduction Techniques

Stress can significantly impact circulatory health. High-stress levels increase cortisol production, leading to various health issues such as high blood pressure, weakened immune function, and poor skin health. Circuhealth Clinic employs several stress reduction techniques to help manage and reduce stress, thereby supporting circulatory health.

For example, the 54321 method is a grounding exercise designed to manage acute stress and reduce anxiety. This method involves identifying five things you can see, four things you can touch, three things you can hear, two things you can smell, and one thing you can taste. This technique can be particularly useful before bedtime to promote relaxation and improve sleep quality.

Other stress reduction techniques include meditation, deep breathing exercises, and yoga. These practices help calm the mind, reduce cortisol levels, and improve overall mental health, supporting better circulatory health.

Importance of a Healthy Diet

A healthy diet is crucial for maintaining good circulatory health. Circuhealth Clinic emphasizes the importance of eating a balanced diet with plenty of fruits, vegetables, whole grains, and lean proteins. Such a diet can help reduce the risk of chronic diseases, improve energy levels, and support overall health.

For those looking to manage hypertension, Circuhealth Clinic suggests a specific dietary approach:

10 Hours Before Bed: No more caffeine.
3 Hours Before Bed: No more food or alcohol.
2 Hours Before Bed: No more work.
1 Hour Before Bed: No more screen time.
0: Number of times you hit the snooze button.

This structured approach helps regulate blood pressure and promotes better sleep, both essential for good circulatory health.

Conclusion

Circuhealth Clinic Clinic, under the expert guidance of Nadia Nassif, offers a holistic approach to health that focuses on improving circulatory health through personalized exercise programs, detoxification treatments, stress reduction techniques, and advanced diagnostics. By addressing the underlying causes of health issues and providing tailored treatment plans, Circuhealth Clinic helps individuals achieve optimal health and well-being.

Whether you are looking to manage a chronic condition, improve your overall health, or simply enhance your quality of life, Circuhealth Clinic’s comprehensive approach offers a path to better health. Embrace these treatments and lifestyle changes to experience the full benefits of improved circulatory health and overall wellness.