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Researchers Find Oral Bacteria Presence in Cerebral Emboli of Stroke Patients

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Scientists at Tampere University analyzed the cerebral emboli (blood clots) of stroke patients’ brains and made an astonishing discovery. For the first time, they discovered DNA from oral pathogens in the cerebral clots.

The findings of the research were published in the May 2019 issue of the prestigious Journal of American Heart Association, reported Science Daily.

When stroke patients came into Emergency Rooms for treatment, neurointerventional radiologists removed the pesky clots known as thrombus aspirates from 75 of these stroke patients. The thrombus aspirates samples were analyzed by the scientists who discovered that 79% of the aspirates contained oral bacterial DNA in them. The samples were analyzed following the duplication of the bacterial DNA.

Tampere University is involved in the study of the consequences of bacterial infection in the development of cardiovascular diseases over the past ten years. Their study is a part of this research project. An older study discovered the same odontogenic bacteria in the coronary artery stenoses of patients who seemed to have suddenly died.

These bacteria were also present in samples taken from:

  • Blood clot blockages and arterial blood of myocardial infarction patients
  • Ruptured weak cerebral blood vessels and blood clot blockages of patients with lower limb arterial and venous thrombosis

Most of these blood clots (thrombi) originate in the carotid artery stenoses of the circulatory system. As blood circulates all the time, the clots break off and travel to block circulation in delicate cerebral arteries. In fact, 87 % of the strokes are caused due to cerebral artery thrombosis.

The new study has discovered a copious amount of viridans streptococcus DNA in cerebral thrombi when compared against normal blood samples taken from the same patient. Viridans Streptococcus is a commonly found oral bacteria. It is completely harmless when present in the oral cavity. However, when streptococci enter the circulatory system, they may cause infection in the cardiac valves, among other things. The bacterium also tends to directly bind with various platelet receptors, thereby enabling more blood clots to form in the bloodstream.

If this research doesn’t encourage you to maintain your oral health and practice good dental hygiene, nothing else will. Untreated dental infections can have a severe effect on your overall health and even cause loss of life. Get your dental problems addressed as soon as possible to lead a healthier and longer life.

Michelle has been a part of the journey ever since Bigtime Daily started. As a strong learner and passionate writer, she contributes her editing skills for the news agency. She also jots down intellectual pieces from categories such as science and health.

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Health

The Scientist as Storyteller: How Steven Quay Makes Complex Medicine Relatable

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Scientific discovery often struggles to reach the people it is meant to serve. The distance between research and public understanding can be vast. For most scientists, publishing in peer-reviewed journals is the endpoint. For Dr. Steven Quay, it is only the beginning. His career has been defined not just by what he has discovered, but by how he communicates it. 

Scientific trust today faces growing skepticism and misinformation spreads faster than facts, Quay has embraced a rare role. He is both a scientist and a storyteller. His ability to bridge the technical and the human is what makes his voice resonate across disciplines, institutions, and communities.

Writing as a Lens into the Human Side of Science

One of the clearest examples of Quay’s narrative instinct lies in his writing. He has authored three major books, each rooted in a different part of his life and expertise. Together, they show how a medical researcher can also be an accessible public thinker.

In Stay Safe: A Physician’s Guide to Survive Coronavirus, published June 5, 2020, during the first days of the pandemic, Quay offered plainspoken, evidence-based guidance on protecting oneself and one’s family. It was not framed as a political statement or a policy directive. It was personal and grounded in the daily realities people faced. He wrote it not just as a scientist, but as someone who wanted to help others navigate a frightening time with clarity and calm.

His second book, The Origin of the Virus, tackled a more complex and controversial subject: the question of how SARS-CoV-2 emerged. Rather than speculate, Quay walked readers through the scientific evidence with the kind of transparency that is often lacking in public discourse. The tone was methodical, never alarmist. What set the book apart was its balance, engaging to a lay reader, yet rigorous enough to be taken seriously by professionals.

Then there is A Ride Through Northville, a deeply personal departure from the world of virology and oncology. Here, Quay revisits his childhood in Michigan, capturing the streets, friendships, and quiet moments that shaped him long before he entered a lab. The structure of the book mimics the experience of riding a bike through town, evoking memory not as a chronology, but as a sensory journey. For a scientist whose career has involved high-stakes research and global debates, this book offers a rare window into the reflective, grounded person behind the work.

Speaking Clearly Without Speaking Down

Quay’s communication skill is not limited to the written word. He has also become a frequent guest on health-focused podcasts and a speaker at public science forums. His TEDx talk on breast cancer prevention is one of the most viewed videos on the subject, and for good reason. He does not rely on drama or abstract theory. Instead, he explains mammographic density, hormonal risk, and clinical trial design in a way that makes the science both comprehensible and actionable.

In interviews, Quay has a habit of slowing things down. He avoids jargon unless he defines it. He is comfortable saying, “We don’t know yet,” which, in the realm of public science, is a kind of honesty that builds trust. He often discusses Atossa Therapeutics’ trials in plain terms, describing how experimental drugs like (Z)-endoxifen might help certain patients respond better to treatment. He emphasizes that these are ongoing studies, not marketing pitches, which sets him apart from many biotech executives.

Educating the Public Without Oversimplifying

One of the challenges of public-facing science is resisting the urge to oversimplify. Many well-intentioned scientists flatten complexity to fit the constraints of social media or mainstream news. Quay does not follow that path. He explains mechanisms and hypotheses with nuance, trusting that readers and listeners are capable of understanding more than they are often given credit for.

His social media presence reflects the same philosophy. He shares articles and research updates, but rarely with alarm or bravado. When he comments on current medical debates, he tends to lead with evidence rather than opinion. That steady tone has earned him a following that spans across ideological and professional divides.

During the pandemic, this approach stood out. While others chased headlines, Quay focused on distilling evolving guidance into practical advice. He acknowledged the limits of current knowledge, updated his views as new data emerged, and emphasized science as an iterative process. His voice became one that many people turned to not for certainty, but for clarity.

A Scientist’s Responsibility Beyond the Lab

Quay has often said that science does not exist in isolation. It is part of society. That belief informs why he writes, speaks, and engages in public discourse as actively as he does. He sees the scientist’s role not just as a producer of knowledge, but as a custodian of its meaning.

He has testified before the U.S. Congress and advised the State Department, not as a politician but as a physician-scientist committed to accuracy. In each case, his contribution has been grounded in data but shaped by a recognition of the human implications of policy and research.

This is especially evident in his work on breast cancer. By advocating for better screening tools and more personalized treatments, Quay speaks not only to clinicians and investors but to women facing real fears about their health. He explains the science behind mammographic density and hormonal modulation not just with charts, but with stories about what those risks mean in someone’s life.

Storytelling as a Form of Service

What makes Quay’s communication style compelling is that it never feels performative. He is not branding himself or building a media empire. He is doing what he believes scientists should do: make their work useful.

In every form of his storytelling, from the deeply personal to the technically specific, there is a throughline of responsibility. He understands that science touches people’s lives in ways that go far beyond the lab. For him, that means speaking clearly, writing honestly, and never underestimating the audience.

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